The Osborn Lab

1. Schlaich MP, Esler MD, Fink GD, Osborn JW, Euler DE. Targeting the sympathetic nervous system: critical issues in patient selection, efficacy, and safety of renal denervation.Hypertension. 2014 Mar;63(3):426-32. [PDF]

 

2. Foss JD, Fink GD, Osborn JW. Reversal of genetic salt-sensitive hypertension by targeted sympathetic ablation. Hypertension. 2013  Apr;61(4):806-11. [PDF]

 

3. Brooks VL, Osborn JW. High-fat food, sympathetic nerve activity, and hypertension: danger soon after the first bite? Hypertension. 2012  Dec;60(6):1387-8. [PDF]

 

4. Veitenheimer BJ, Engeland WC, Guzman PA, Fink GD, Osborn JW. Effect of global and regional sympathetic blockade on arterial pressure  during water deprivation in conscious rats. Am J Physiol Heart Circ Physiol. 2012 [PDF]

 

5. Averina V, Othmer H, Fink GD and Osborn JW. A new conceptual paradigm for the hemodynamics of salt-sensitive hypertension: a mathematical modeling approach. J. Physiol., 590(23), 5975-5992, 2012 [PDF]

 

6. Kuroki M., Fink GD and Osborn JW. Time dependent changes in autonomic control of splanchnic vascular resistance and heart rate in AngII-salt hypertension. Am. J. Physiol. 302: H763-H769, 2012. [PDF]

 

7. Osborn JW, Fink, GD and Kuroki M. Neural mechanisms of angiotensin II-salt hypertension: Implications for therapies targeting neural control of the splanchnic circulation. Current Hypertension Reports, 13:221-228, 2011. [PDF]

 

8. Charkoudian N., Gusman E,  Joyner MJ,  Wallin BG and Osborn JW. Integrative mechanisms of blood pressure regulation in humans and rats: cross-species similarities. Am. J. Physiol. 298: R755-R759, 2010. [PDF]

 

9. Abrams J, Engeland W and Osborn JW. Effect of intracerebroventricular benzamil on cardiovascular and central autonomic responses to DOCA-salt treatment. Am. J. Physiol. 299: 1500-1510, 2010. [PDF]

 

10. Yoshimoto M, Miki K, Fink GD, King A and Osborn JW. Chronic angiotensin II infusion causes differential responses of regional sympathetic activity in rats. Hypertension, 55: 644-651, 2010. [PDF]

 

11. Osborn JW,  Fink GD, Sved AF, Toney GM and Raizada MK. Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension. Current Hypertension Reports. 9: 228-235, 2007. [PDF]

 

12. Osborn J.W. Set points and long-term control of arterial pressure: A theoretical argument for a long-term arterial pressure control system in the brain rather than the kidney. Clin. Exp. Physiol. Pharmacol. 32:384-394, 2005. [PDF]

 

13. Osborn JW, Jacob F and Guzman P. A neural set point for long-term control of arterial pressure: beyond the arterial baroreceptor reflex. Am. J. Physiol. 288:R846-R855, 2005. [PDF]

 

14. Jacob F, Ariza P and Osborn JW. Renal denervation chronically lowers arterial pressure independent of salt intake in normal rats. Am. J. Physiol., 284:H2302-H2310, 2003. [PDF]

 

15. Osborn JW and Hornfeldt BJ. Arterial baroreceptor denervation impairs long-term control of arterial pressure during dietary salt loading Am. J. Physiol. 275:H I 558-H1566, 1998. [PDF]

 

16. Osborn JW and England SK. Normalization of arterial pressure after barodenervation: Role of pressure natriuresis. Am. J. Physiol. 259:R 1172-R1180, 1990. [PDF]